On OSX, hit CMD-Space to open spotlight.
Type search word, and it’ll also search obsidian vault aliases.
On install, add Obsidian as a search engine in spotlight.
http://flashlight.nateparrott.com/ installs other search tools.
Open Obsidian and search there - but it’s not yet always the only/first thing I search.
You might want to check this out:
It lets you easily open different vaults, but I’m not sure if that is what you’re looking for.
Thanks!
Alfred seems to crash my Mac a lot more than usual; or so I think, anyway.
I might try again; it was very cool.
That’s too bad. I haven’t had any issues with Alfred and I use it a lot. I hope your issues go away soon. 
Since Sep 13, 2020, Alfred has been used 19,087 times. Average 100.5 times per day.
Would be extremely useful
Raycast is also an option
Seconded.
This appears to be the current solution for Raycast:
Related: