Electron apps are not compatible with many OS features without significant effort to set them up, as far as I understand.
I have not used Zotpick, though, so I have no idea how it works. The readme says it should “work with any app.” I imagine that this line…
- If you use an app-launching utility that lets you assign key combos to apps, use that to launch these scripts.
…means that you should be able to call Zotpick with e.g. Alfred or Keyboard Maestro. Have you tried that?