I keep one of my vaults (used daily) in OneDrive and generally have no issues*, although I do get the occasional numbered settings files, e.g. workspace-PC-NAME-2.json.
The important thing to remember/set using OneDrive, or any of these cloud services, is to keep the vault or the folder it’s in always local and downloaded to each device you are using Obsidian on. If the service arbitrarily decides to remove files or folders in your vault, Obsidian is going to have a problem.
* Two or three times this setting was forgotten or reset during an OS or OneDrive update for me.
You may want to move your vault of out OneDrive, but I’m just sharing my experience that it’s generally fine.
Also sync ≠ backup, so you’ll want to have a backup system in place if you don’t have one already.
As for plugin issues, the troubleshooting steps are here: