I think the two answers above are talking about moving your vault.
But you’re asking about the folder in C:\Users\You\AppData\Roaming\obsidian which is more related to app settings, or caches or what not.
And that answer is different. You might want to look into how people install Obsidian in portable mode. Search results for 'portable' - Obsidian Forum
Or how people are discussing or requesting the ability to choose where it installs: Controlling installation location
Also how big is the folder getting? Can you spot any abnormally large files? Maybe there is a bug. Maybe it is safe to delete that file and reset whatever caching/indexing is happening. (But I don’t know. Backup first if you try that!)