Running Obsidian from external drive

I am trying to run Obsidian from an external/portable USB drive (or at least have the data file stored there). I tried moving the data files to the drive and was able to access without any issues. However, after rebooting, I can no longer access the vault. I get permission errors. It is as though Obsidian cannot read/write to that drive. Any advice on how to set the app up to run on the external drive?

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Hard to say, not knowing what operating system you’re using.

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